Budd Chiari syndrome associated with Antithrombin III and Protein S deficiency, a case report

Authors

DOI:

https://doi.org/10.35622/j.ram.2023.01.007

Keywords:

Budd Chari, hypersplenism, antithrombin III, protein S, thrombophilia

Abstract

Budd Chari syndrome is a rare pathology characterized by obstruction of the venous flow of the liver, caused by thrombosis as a consequence of thrombophilia, myeloproliferative disorders, cancer, infections, or any disorder that obstructs the flow of the portal vein. The case was presented in a 21-year-old man who debuted with upper gastrointestinal bleeding, associated with esophageal varices and hypersplenism. In this patient, anticoagulation was started after ligation of esophageal varices, and after splenectomy, due to its association with thrombocytopenia, which subsequently increased, starting with low molecular weight heparin and later factor Xa inhibitors. (Rivaroxaban 20 mg) every day with good tolerance is discharged in good clinical condition. Timely diagnosis and treatment represent a challenge for the prognosis of patients.

Author Biography

  • Danny Silva, University of Guayaquil

    Médico Especialista Medina Interna, Jefe área de Emergencias en el Hospital Clínica Guayaquil, en Ecuador.

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Published

2023-01-31

Issue

Vol. 2 No. 1 (2023)

Section

Case reports

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Copyright (c) 2023 Danny Silva Cevallos, FERNANDO SILVA , VELIMIR FLORES , JUAN SALAZAR, DIANA SALAZAR, CAMILO NEVAREZ, MICHELLE LOPEZ

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Silva, D., Ordoñez, C., Silva, F., Loor, C., Nevarez, C., Salazar, J., Salazar, D., Guallpa, J., & Quintero, L. (2023). Budd Chiari syndrome associated with Antithrombin III and Protein S deficiency, a case report. Revista Acciones Médicas, 2(1), 76-85. https://doi.org/10.35622/j.ram.2023.01.007

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